Sleep disorder in Angelman syndrome: causes, mechanisms and methods of correction. Literature review

Sleep disorder is one of the prominent manifestations Angelman syndrome. The exact causes are unknown and methods correction difficult. literature review devoted to studies pathogenesis sleep disorders in syndrome (the effects gene function 15q11–q13 deletion, findings polysomnography, video-EEG monitoring, laboratory data), on basis which recommendations for dyssomnia, including behavioral therapy, given.